BIOC33H3 Lecture Notes - Bronchus, Brainstem, Mesothelioma
Document Summary
Lungs, thoracic cavity and pleura: lungs sit in the thoracic cavity - comprised of ribs, sternum, intercostal muscles, diaphragm, diaphragm = major respiratory muscle, each individual lung is situated within a pleural sac. Pleural sac consists of 2 linings: visceral pleura - sits right on top of lung tissue, parietal pleura - annealed to chest walls; ribs and muscles. In between the two, small pleural space - interpleural fluid. Fluid is important to keep these 2 linings together. Important pressure differences: 3 important pressures. Under resting conditions, is the same as: changes over course of inspiration allowing air in and expiration to allow air out, only manipulate this. Palv pip = transpulmonary pressure: driving force for lung expansion. Patm palv: driving force for air flow into or out of the lungs. Ideal gas law: 2 components to air flow that are important: Pressure gradient driving air in and out of lungs.
