BIOC19H3 Lecture Notes - Lecture 2: Interphase, Blastula, Spermatogonium

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But the changes in cellular process and functions are not obvious. What is specification: can differentiating by itself (autonomously) in a developmentally neutral environment (not receive any external stimulus) Example: a cell specified to be a muscle cell will grow as such unless placed in a different environment: if place the cell in population of differently specified cells interaction with neighbours will determine cell fate by: The muscles cell become neuron because it is placed with the neuron cell (cell fate of the muscle cell changed because it got cell signal from neuron) Specification by differential acquisition of certain cytoplasmic molecules present in the egg . 1. the environment of the cell determines its fate it is the process by which cells achieve their respective fates by interacting with other cells. Position of cells relative to each other are keys . Specification by interaction between nuclei and cytoplasmic determinant prior to cellularization of the blastoderm .

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