BIOB34H3 Lecture 4: Lecture 4

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By the process of most of the atp cell produce occur in mitochondria phosphorylation. 2 components to oxidative phosphorylation: electron transport chain. To oxygen in that process, energy is released - which is used by etc complexes to pump protons across the inner mitochondrial membrane & thus create a proton gradient: atp synthase. Reality when this happens, proton leak occurring, the etc has to start working more (pump protons) To compensate for that leak -- accounting for 18% of animals bmr/smr. 40% of an animal"s bmr/smr is some way related to the leakiness of cellular membranes (pump protons/pump ions) The composition/properties of cell membranes set the metabolic pace - metabolic rate largely determined by the nature of the cell"s membrane & how leaky they are to proton/ions major component that makes up cell membrane phospholipids. 2 carbons of glycerol attached to fatty acids.

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