HSS 4102 Lecture Notes - Lecture 2: Insulin-Like Growth Factor 1, Neurodegeneration, Myostatin

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 4102
• Professor: Ron Saulnier

Document Summary

Lecture 2: environmental epigenetics how agents in the environment affect molecular changes in. Environmental agents alter phenotypes by altering gene expression during development in one of three ways: direct transcriptional regulation, the neuroendocrine system, direct induction. Every cell in the body contains the exact same dna but there are over 100 different types of cells in the body. It is the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. The study of chromatin alterations that result in changing the stable, long-term changes in the transcriptional potential of cells. Biological dogma genetics governs all the inherited traits across generations, and epigenetic modifications are reset upon passage through the germ line. Although the chromosomes in our genome carry the genetic information, the epigenome is responsible for the functional use and stability of that information and connects the genotype with the phenotype.