HSS 3305 Lecture Notes - Lecture 16: Thrombocytopenia, Skeleton, Haemophilia A

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 3305
• Professor: Karen Phillips

Document Summary

Blood pressure (bp): created by pumping action of heart; in arteries, bp rises during ventricular systole and falls during ventricular diastole. Cardiac output (co): volume of blood pumped per minute (determined by heart rate and stroke volume: amount of blood pumped by ventricle in one contraction) Peripheral resistance: friction in arteries as blood flows through. Blood volume: amount of blood in vascular system. Systolic blood pressure is consistently over 140 (systolic is the top number; represents the pressure generated when the heart beats) Diastolic blood pressure is consistently over 90 (diastolic is the bottom number; represents the pressure in the vessels when the heart is at rest) Cardia effects enlarged heart may function effectively for years cardiac failure. Vascular effects hypertension accelerates development of atherosclerosis in larger arteries, cerebral hemorrhage complication of severe hypertension. Renal effects narrowing of renal arterioles decreases blood supply to kidneys kidney failure. Mutations in the scnn1b or scnn1g gene.