ANP 1107 Lecture Notes - Lecture 8: Acetyl-Coa, Citric Acid Cycle, Oxidative Phosphorylation

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jacqueline Carnegie

Document Summary

2. 1 review the metabolic pathways and their interactions. Used to: (i) construct bodies molecules (ii) generate energy mostly in the form of atp through cellular respiration. Redox reactions: oxidation (losing electrons) and reduction (gaining electrons) Carbohydrates: metabolized first via glycolysis; produces some energy via substrate-level phosphorylation, typically followed by the kreb"s cycle; produces some atp via substrate-level phosphorylation. Motor in atp synthase which converts adp + pi to atp reverse proton pump. Fats: fat very efficient energy store; ~2x versus glycogen, both glycerol and free fatty acid side chains can be used for energy. Both fatty acids and glycerol products can enter krebs cycle: b-oxidation (2 carbon ) of fatty acids yields acetic acid which is converted to acetyl coa . Krebs: fatty acids cannot be used to generate glucose via gluconeogenesis. 2. 2 define the absorptive state and the key role of insulin in its metabolic regulation. Insulin directs essentially all events of absorptive state.