ANP 1106 Lecture Notes - Lecture 13: Afferent Nerve Fiber, Amyotrophic Lateral Sclerosis, Substantia Nigra

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Middle: motor cortex (pyramidal system) and brain stem nuclei. The cortex sends direct (corticospinal) and indirect (corticobulba/bulbospinal) projections to the spinal cord: damage: paralysis. Movement is initiation in the basal ganglia which then projects to the motor cortex (movement execution: lesions: akinesia (difficult to initiate movement) Movement is regulated by the cerebellum which then projects to the motor cortex: lesions: dyskinesia (uncoordinated movement) Primary motor cortex: precentral gyrus of the frontal lobe. Premotor cortex: anterior to precentral gyrus: coordinates movement of several muscle groups simultaneously, even just thinking about movement causes activity to appear in the premotor cortex. Broca"s area: one side only: motor speech area. Frontal eye field: voluntary movements of the eyes. Deliver efferent impulses from the brain to the spinal cord and are divided into two groups: direct pathways are equivalent to the pyramidal tracts: no synapse in the brain stem.

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