ANP 1105 Lecture Notes - Lecture 2: Urinary Incontinence, Oligodendrocyte, Electrochemical Gradient

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Qiao Li

Document Summary

Integral membrane proteins span plasma membrane: hydrophilic & hydrophobic regions; channels, transporters, carriers, receptors, enzymes. Pm: glycocalyx changes when cell becomes cancerous - can even change repeatedly to avoid recogniion by immune system, cholesterol: impacts membrane luidity. Each channel is coded by its own gene. It ilters out all ions except the selected ones. The inside of the cell is hydrophilic, outside is hydrophobic. Voltage sensing occurs (channels opening depending on polarity) Enzymaic process: pump ions against concentraion gradient using atp. Cell fusion mediated by integral membrane proteins of pm in adjacent cells to form inpermeable juncions. Prevent passage of molecules through extra-cellular space between adjacent cells. Anchoring juncions: molecular linking of cells to resist mechanical stress. Molecular channels between cells to allow passage of cytoplasmic molecules. Funcions of the plasma membrane: efecive barrier between the intracellular & extracellular luids, signal transducion, allows the cell to respond to changes in the extracellular luid, site of cell-to-cell interacion and recogniion.