NURS2132 Lecture Notes - Lecture 13: Phenoxymethylpenicillin, Cefazolin, Sulfamethoxazole
Document Summary
Inhibits protein synthesis in susceptible bacteria: bacteriostatic, work similarly to tetracyclines. Also bind to ribosomes and prevent protein synthesis in bacteria: bactericidal, destroy bacteria by altering their. Cephalosporin (penicillin g, penicillin v: bactericidal antibiotic kill variety of gram- positive and negative bacteria. Inhibition of bacterial wall synthesis (cefazolin: bactericidal. Bind to same penicillin- binding proteins inside bacteria inhibiting cell wall synthesis (sulfamethoxazole) Action: bacteriostatic antibiotics do not kill the bacteria, but inhibits growth, most often used in combination with another antibiotic (trimethoprim) for a synergistic drug effect. Smx-tmp: when given in combination, they inhibit two successive steps in the bacterial folic acid pathway which enables an additive antibacterial effect. Utis: respiratory, skin, gi, bone, joint infections and stis involving the gi or gu tract. In children pneumonia, meningitis, utis: drug allergy, same as. Penicillin: drug allergy, pregnancy and breastfeeding, children under.
