PHRM 211 Lecture Notes - Lecture 18: American Ginseng, Panax Ginseng, Immunostimulant
Document Summary
Treatment reduce duration (some evidence); 2g/day more effective than 1g/d. Prevention does not decrease number of colds. Adverse effects diarrhea & kidney stones (at higher doses: 1-3 g/day) May provide benefit in people under physical stress not under normal conditions. Eleutherococcus senticosus (siberian) not a true ginseng. Polysaccharides & oligosaccharides believed to have immune-modulating effects: quinquefolium nk cell activity and antibody response to vaccination, ginseng (korean red) Significantly less acute respiratory infections (ari) in ginseng group vs placebo. No change in symptoms or severity: quinquefolium. Helps reduce frequency, severity and duration of cold and flu symptoms. 200 mg (rich in polysaccharides extract from the root of p. quinquefolius) Dose: 1-2 caps po bid x duration of cold. Intended to imitate cold-fx: quinquefolius root extract standardized to 4% ginsenosides. Never been allowed to market as having immediate relief . Vaccinated healthy seniors no change in resp sx, ari. 4 months treatment # of colds, total symptom days.
