PSYCH291 Lecture Notes - Lecture 7: United States Public Health Service, Institutional Review Board, Nuremberg Code

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Three core principles (see parallel principles in table 4. 1: respect for persons, concern for welfare. Tuskegee syphilis study (1932-1972): us public health service research study, 600 low-income african-american males in alabama monitored for 40 years, 400 infected with syphilis, goal was to study effects of untreated s(cid:455)philis o(cid:374) (cid:373)e(cid:374)"s health. Told the(cid:455) (cid:449)ere (cid:271)ei(cid:374)g treated for (cid:862)(cid:271)ad (cid:271)lood(cid:863) free medical examinations to a low income group of people, takes advantage of vulnerable people. In 1947 proven cure (penicillin) discovered but study continued until 1972 with participants being denied treatment. Formal apology delivered by bill clinton in 1997. It should be the last resort, not common, need ethics approval: must balance risks and benefits, minimal risk/stress- the study gives no more risk than what participant would experience in everyday life. Relation to core principle: concern for welfare researcher must carefully balance risk and benefit. **** this is often not an easy decision. Respect for persons: decision to participate up to participant.

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