PSYCH261 Lecture Notes - Lecture 18: Heritability, Serotonin Transporter, Prefrontal Cortex

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Postsynaptic cell releases retrograde transmitter which goes back to the presynaptic cell. Expansion of axons (surface area) get more larger terminal buttons to release additional transmitters more sites to receive transmitters from the postsynaptic cells more collateral sprouting. Little energy, worthlessness, suicidal thoughts, hopelessness, little pleasure. Females more likely than males to experience major depression (go down as you get a little bit older) People with the genes for major depression are predisposed to other kinds of diseases. Anxiety disorders, add, ocd, substance-abuse disorders, etc. Women (elevated risk of depression when it occurs before the age of 30) Serotonin transporter protein (controls reuptake of serotonin) As number of stressful life events increases, the more likelihood you have of developing depression. 2 short forms of gene (much more likely to experience depression due to stressful life events) Viral infection (depression can be carried by a virus very uncommon/unlikely borna disease)

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