KIN406 Lecture Notes - Lecture 4: Pax7, Myosatellite Cell, Cdk Inhibitor
13 Mar 2017
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If it does not get the signal it will not divide: when a protein is phosphorylated the function changes and thus the signal can change, those things are still there but maybe not at the level needed. G1 m: cell cycle (cid:498)checkpoints(cid:499) are safeguards to ensure the events of the previous phase have been completed correctly and are found at the g1 to s and g2 to m transition. Cell proliferation & hayflick limit: regardless of the expression level of proteins and factors that promote proliferation, cells have a finite number of cellular divisions. Cell cycle and mitosis: the dna polymerase adds new nucleotides upstream of the primer in the. Insertion of telomere nucleotides by telomerase another hexanucleotide sequence and the process repeats: now when the dna is replicated, only junk dna is lost. Satellite cell markers: regenerating muscle fiber showing centralized nuclei (blue dapi) and activated satellite cell (red - m-
