KIN404 Lecture Notes - Lecture 3: Corticotropin-Releasing Hormone, Neuropeptide, Cannabinoid
29 Jan 2019
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Kin 404 section 1 regulation of energy intake lecture 3. Brain neuropeptides and their influences on food intake & energy expenditure. Signalling modality within brain centres of energy balance regulation is via chemical synapses. Chemical neurotransmission uses neurotransmitters and neuropeptides released from synaptic vesicles of axon terminals and their respective receptors located on the postsynaptic membrane or membranes of adjacent axon terminals. Central regulation of feeding behaviour and energy expenditure relies on the appropriate interaction between particular neuropeptides. These neuropeptides always have opposite effect on food intake and energy expenditure. Some ghrelin is produced in the brain (hypothalamus) but this course is focusing on the ones produced in the gut. Central nervous system centres of appetite control & the pathways by which circulating. @ brainstem & the media eminence (me) @ hypothalamus do not have a complete blood barrier. Ap & me are susceptible to influence by blood-borne signal (signal carried by the blood)
