BIOL442 Lecture Notes - Lecture 6: Bunyavirales, Polydnavirus, Paramyxoviridae
16 Jul 2014
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Negative strand rna animal virus: a) b) c) d) e) f) Give an example of a virus from this family. Animal (-) strand rna viruses, plants and some insect dna viruses. Nucleic acids that are very long are more subject to physical damage, especially when ss; many small pieces is more stable. Rna more labile than dna (degrades very easily) Ss genomes have no way to repair themselves (no template) All the segments must get made and packaged. Genome divided into 2 or more physically separate molecules of nucleic acid. Hiv has two identical copies of (+) strand genome, but this is not the same as segmented. Packaging of a specific designated segment occurs first. Only when this occurs, then next designated segment enters then next, etc. Ratio of total virus particles: infectious particles = 1. A proportion will have the correct number of segments. Ratio of total virus particles: infectious particles = large.
