BIOL308 Lecture Notes - Lecture 5: Xeroderma Pigmentosum, Dna Mismatch Repair, Pyrimidine Dimer
Document Summary
Distinguish between the terms mutation , dna repair and. In most cases, dna changes either have no effect or cause harm, but occasionally a mutation can improve an organism"s chance of surviving and passing the beneficial change on to its descendants. Recombination: reassortment of genes or alleles in new combinations. Dna repair: dna repair is a collection of processes by which a cell identifies and corrects damage to the dna molecules that encode its genome: list and briefly explain three major causes for mutation in dna. Dna-> loss in nucleotide) , c deamination : c--> u, others including. Ionizing radiation (x rays and gamma rays): double strand breaks: base analogues: 5 bromouracil=t and replaces it. If the mutation occurred in a germ cell or germ cell precursor disease predisposition may be(come) hereditary the mutated dna will form the original template used to make the dna in the other cells and will therefore be passed on.