BIOL273 Lecture Notes - Lecture 14: Aorta, Coronary Circulation, Pulmonary Artery
6 Jul 2018
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Lecture 14
- Major material transported: Oxygen (CVD closely tied to respiratory system)
Many cells absolutely require oxygen to survive – 02 is required by vas
majority to perform oxidative metabolism within the mitochondria in the
cells
Lack of oxygen causes irreparable damage
Brain the most oxygen dependent organ in human body – doesn’t take
very long to exhibit symptoms of 02 deprivation
o5-10 sec of interrupted blood flow results in loss of
consciousness, might feel dizzy
o5-10 min interrupted blood flow permanent brain damage, those
regions which don’t get 02 will get deprived and permanently
damaged
Q: Which of the following is a feature in cardiac muscle cells?
A: Striations. Cardiac and skeletal both, the sarcomere arrange with the light dark
patterns,
Not multiple nuclei – skeletal has this
Not all-or-none contractions – also skeletal (with smooth we have diff
contraction levels)
Not spindle shaped fibers – smooth muscles
⌘Components of the Cardiovascular System
A. Components
- Heart pump
It is going to increase pressure of blood found inside the chamber and this
is the driving force of the bulk force of blood out of the heart
- Blood vessels vasculature
See exchange of materials here
- Blood cells and plasma fluid
Ground substance, which is plasma, and then you have the cellular
components
Blood is a very bright fluid, reddish, which comes from the erythrocytes –
RBCs, if you spun it in a centrifuge you separate the densities (separate
whole blood)
RBCs are the most dense so they are at the bottom of the capillary tube
At the top you have plasma which is essentially water, proteins,
electrolytes, ions, etc
In the middle of plasma and RBC you have circulating white blood cells,
which is called the ‘buffy coat’ – a very thin layer. These are white blood
cells required for immune systems, so they don’t stay in the blood stream
of very long so they move out and go to different parts of the body.
oNeutrophils, eosinophils, basophils, lymphocytes
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Document Summary
Major material transported: oxygen (cvd closely tied to respiratory system) Many cells absolutely require oxygen to survive 02 is required by vas majority to perform oxidative metabolism within the mitochondria in the cells. Cardiac and skeletal both, the sarcomere arrange with the light dark patterns, Not multiple nuclei skeletal has this. Not all-or-none contractions also skeletal (with smooth we have diff contraction levels) Not spindle shaped fibers smooth muscles. Components of the cardiovascular system: components. It is going to increase pressure of blood found inside the chamber and this is the driving force of the bulk force of blood out of the heart. Ground substance, which is plasma, and then you have the cellular components. Blood is a very bright fluid, reddish, which comes from the erythrocytes . Rbcs, if you spun it in a centrifuge you separate the densities (separate whole blood) Rbcs are the most dense so they are at the bottom of the capillary tube.
