BIOL273 Lecture Notes - Lecture 15: Pericardium, Arteriole, Coronary Circulation

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Lecture 15
C. Path of Blood in Systematic Circulation
- Aorta carries oxygenated blood from the heart
- Arteries branch into series of smaller arteries that lead into capillaries
Capillaries are thin walled vessels that allow exchange of materials
Capillary beds are all throughout the body and cells can’t be too far away
form the body and oxygen can diffuse so far before you lose the ability of a
good rate of diffusion – same thing with C02.
So you need capillaries for exchange of material efficiently
- Blood in capillaries move into small veins & then larger veins
Which bring the blood back in to the systemic circulation
The Heart
A. Introduction to the Heart
- Divided (functionally) into two separate pumps that work in series
Blood travels in one pump and then go to the next part of the circuit.
Arteries away, veins towards
- In the body the separate pumps are next to each other in one organ, and pump
together simultaneously
- Blood vessels:
Arteries  carry blood away from the ‘pump’ into the aorta – you will
decrease in pressure as blood moves away from the heart – very low in the
capillary beds
Veins  return blood to the ‘pump’
- Exit from heart (highest pressure)  blood vessels (low pressures)  entrance to
heart (lowest pressure)
Pressure at it highest when in the pulmonary trunk and low in vessels and
lowest when back into the heart
So pump 1 leads in a circuit goes to pump 2 and then goes back to pump 1 – a
continuation – 2 separate pumps in series but anatomically they are side by
side: left side and right side work in unison with contraction and relaxation
Question: Why have two pumps in series?
Answer: Think about what happens as blood travels through the body
Pump #1  contracts (decreases in volume) – heart to lungs
oIncreases the pressure and pumps blood into the lungs (pulmonary
circulation)
oBlood picks up oxygen for transport to the rest of the body
oLungs contain very many small capillaries to increase O2 transfer
oSmall radius, high surface area  increase resistance  decrease
pressure
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Document Summary

Lecture 15: path of blood in systematic circulation. Aorta carries oxygenated blood from the heart. Arteries branch into series of smaller arteries that lead into capillaries. Capillaries are thin walled vessels that allow exchange of materials. Capillary beds are all throughout the body and cells can"t be too far away form the body and oxygen can diffuse so far before you lose the ability of a good rate of diffusion same thing with c02. So you need capillaries for exchange of material efficiently. Blood in capillaries move into small veins & then larger veins. Which bring the blood back in to the systemic circulation. The heart: introduction to the heart. Divided (functionally) into two separate pumps that work in series. Blood travels in one pump and then go to the next part of the circuit. In the body the separate pumps are next to each other in one organ, and pump together simultaneously.

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