BIOL130 Lecture 20: BIOL 130 – Week Ten Notes (Cytoskeleton - LEC 20)

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A network of fibers forming scaffolding" within cytoplasm. Allows movement of organelles / components within cells: coordinates movement of chromosomes during mitosis. Allows movement of cells themselves ( motility": forms flagella, cilia, lamellipodia. Serves as both bones" and muscles" of the cell. Once thought to be the feature of eukaryotes only. However recent advances in microscopy have shown that analogs of all the major cytoskeletal elements (including proteins) exist in prokaryotes as well: they play a similar role too cell shape, division, polarity, e. t. c. What are the 3 main types of cytoskeletal filaments: microtubules thickest and radiate out (drag along membrane components. 2. with this, organize endomembrane components like er and golgi as well. Intermediate filaments consist of long, twisted strands look like they are hooking up with each other: microfilaments (actin) thinnest. Strands of consist of long fibrous proteins, each with globular n-terminal head, globular c-terminal tail and -helical rod domain.

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