BIOL130 Lecture : Biol130 - Unit10&11 Cytoskeleton & Social Context.pdf
11 Dec 2013
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Contaisn aa"s: --> hydroxyl, proline, hydroxyl lysine. Pluripotent - capable of giving rise to several diff cell types. Original egg divides several times all containing same genome but different patterns of genes --> proteins. Cells found throughout the body that divide to replenish dying cells and replenish damaged tissues. A network of fibres forming structures within the cytoplasm. Determines cell shape, position of organelles, movement or organelles and cells. Even intermediate filaments in the same organism can have different. Keratins - most diverse class of intermediate filaments proteins. How they are made tubulin heterodimer is a microtubule subunit - dimer of alpha and beta. Dimers polymerize spontaneously forming plus and minus end strand - protofilament. Dynamic microtubules: cell shape, movement, spindle fibres. For movement of molecules, microtubules are the railing, motor proteins are the engine: microfilaments. Intestinal lining: model system for epithelium and extracellular matrix. Large amounts of extracellular matrix - gives strength.
