PATH 205.3 Lecture 6: Blood and Lymphoid systems
Document Summary
Cells (45%: red blood cells (erythrocytes): 4. 5 million/mcl, white blood cells (leukocytes): 5,000- 10,000 mcl: granulocytes, neutrophils (60%-70%, eosinophils (1%-3%, basophils (1%, monocytes (4%-8%, lymphocytes (20%-40%, platelets (thrombocytes): 150,000- Plasma (55%: water (92%, proteins (7%, albumin. Immunoglobulins: clotting factors, enzymes, transport proteins, salts, lipids, cholesterol, carbohydrates, glucose, gases, oxygen, carbon dioxide. White blood cells participate in the (cid:271)ody"s defe(cid:374)se against infections: granulocytes, neutrophil: Are short-lived, no more than 4 days. Fight infection by responding to chemotactic stimuli. Phagocytosis and release bactericidal substances: eosinophil: only 1-3%, function in allergic reactions. Function in parasitic infections: basophil: function in allergic reactions (hay fever), Contain histamine, serotonin and heparin which increase permeability: monocytes = 4-8%, precursors of tissue macrophages. Long lived: lymphocytes = 40% of white blood cells. T cells: peripheral lymphocytes; attack foreign cells, cancer cells, and cells infected with a virus. Platelets (thrombocytes) = are cells that are essential in the clotting process.
