MBIO 1010 Lecture Notes - Lecture 20: Mucous Membrane, Antimicrobial Peptides, Goblet Cell
8 May 2017
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Document Summary
Protect infectious diseases from most: exists at birth and always present, natural host resistance. No memory: can be specific for tissue. Chemical + physical barriers, special immune system cells, physiological processes and molecular defenses. Opening to the interior of the body mucosal membrane. Lysosome attacks the peptidoglycan of bacteria (sweat, salvia, tears) Cell layers thick) but the tight junctions are clipped together by protein multiples in the plasma membranes so they are close together so no bacteria or other things get inside the body. Susceptibility to pathogens varies from species to species. Anthrax: fatal blood infection in cattles vs cutaneous in humans. Pathogens prefer a specific body site to initiate infection. Things like hiv virus can only attack humans therefore we have different immune systems. We evolve to understand our predators so we have immune systems in place that can resist this. Cyris membrane no opening to the outside (eg. peritoneum)
