BIOL 2500 Lecture Notes - Lecture 14: Complementary Dna, Polynucleotide, Chromatin
14 Mar 2017
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Document Summary
Dna is the hereditary molecule of life: the term hereditary molecule means a molecular substance that carries and conveys the genetic information of a species. Chromosomes contain dna: dna was first noticed in 1869 when friedrich meischer isolated it from nuclei of white blood cells, he called it nuclein. In the 1870s, microscopic studies identified fusion of male and female nuclei during reproduction and chromosomes were observed soon after. Early suggestion that dna was the hereditary material. In 1903, walter sutton and theodor boveri independently described the parallels between chromosome partitioning into gametes and the inheritance of genes. Focus on the nucleus and chromosomes: by 1920, dna was identified as the principal component of nuclein, the basic chemistry of dna was deciphered. It is a polynucleotide consisting of 4 repeating subunits, adenine, thymine, cytosine, and guanine, held together by covalent bonds.
