PSYC 1000 Lecture Notes - Lecture 16: Leptin, Blood Sugar, Ghrelin
Document Summary
States of internal tension that motivates behaviour to reduce the tension. Horny, hungry, thirsty, tired, lonely, poor, dirty, cold, hot, in danger. These trigger empathy when we see others going through these. State of physiological equilibrium that the body strives to maintain. Ex: indoor temperature regulation: thermometer (sensor)---thermostat (control centre)---furnace (response system)---temperature (internal state) Ex: body energy regulation: gut and brain (sensor)---brain (control centre)---eat/convert stored energy (response system)---energy (internal state, gut describes digestive system. Glucose (in blood stream) sensors (on liver, in brain) When blood glucose levels decrease: liver converts stored nutrients to glucose, hypothalamus triggers hunger. When blood glucose levels increase: liver stops converting stored nutrients, hypothalamus triggers satiety (being full) Level of circulating leptin is proportional to the total amount of fat in the body. Mutations that affect leptin productions or reception. Hypothalamus is getting bad reception (it thinks you have no stored fat) This can be treated using genetic therapies (for leptin system)