PATH 3610 Lecture Notes - Lecture 1: Male Accessory Gland, Sertoli Cell, Leydig Cell
28 Sep 2017
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Makes embryonic gonads become testes release testosterone- develop male accessory sex organs + genitalia, without testes female accessory sex organs. Organism functions so genes can survive reproduction essential life function. Zygote gets 23 from mom and 23 from dad 23 homologous chromosomes pair of chromosomes contain similar genes first 22 = autosomal chromosomes and 1 is sex chromosomes. Genomic imprinting epigenetic changes in zygote due to silencing allele from one parent and expression of only the non imprinted allele of the other parent in offspring these genes are susceptible to mutations that can cause diseases. Sex chrom #23 female xx and male xy. Dna of y chrom includes x transposed sequences identical to regions of x chromosomes y is evolved. X chromosome inactivation one x active only in two x chrom of woman- cells mosaidc in which active. X chrom may be derived from either parent inactive clump = barr body cheek cells.
