NUTR 3210 Lecture Notes - Lecture 13: Acetyl-Coa, Urea Cycle, Nitrogen Cycle
Document Summary
Protein is the dietary source of nitrogen, and nitrogen balance has traditionally been the primary method f determining protein requirements in human. Is a measure of nitrogen input relative to losses, which is an indicator of protein metabolism. Nitrogen intake (diet) nitrogen output/losses (in urine/feces) Nitrogen balance may be positive, negative, or zero. Positive: aa are incorporated into protein during growth. Negative: starvation, excrete more nitrogen than ingested because the body is breaking down tissue proteins. Phosphorylation: addition of pi to a protein. Hydroxylation: addition of oh, requires vitamin c and copper. The majority of dietary amino acids are resynthesized into new proteins. The rest are used for atp production: ammonia is taken off (nh3) and the rest are used to make energy. Acetyl coa, glucose, glycogen, triglyceride: ammonia can be turned into ammonium which can go to the kidney and excreted in urine, ammonia goes to the liver and through the urea cycle.