MICR 2420 Lecture Notes - Lecture 1: Microorganism, Frederick Griffith, Genome Size
23 Oct 2017
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Treponema pallidum is small, spiral-shaped bacterium that causes the std syphilis. The microbe is very fragile and can only survive inside the human body. Ignaz semmelweist (1818-1865) was the first proponent of hand-washing as an important process for physicians in hospitals: sterilization in hospitals will improve health. Pioneered the use of a clean (free-form microbes) operating area for his patients: started to use chemicals (carbonic acid spray) Aspeptic chemicals that kill the microbes cannot be take internally, they would kill the host too. Leads to a sear(cid:272)h for (cid:862)(cid:373)agi(cid:272) (cid:271)ullet(cid:863) (cid:449)hi(cid:272)h (cid:272)a(cid:374) kill o(cid:374)ly the (cid:373)i(cid:272)ro(cid:271)es, disease (cid:272)ausi(cid:374)g agents. Accidental discovery of penicilin, from pencilium notatum against staphylococcus by. In 1941, howard florey & ernst chain purified pencilin inhibits formation of bacterial cell wall. Alexandar fleming (1881-1955): (cid:862)o(cid:374)e so(cid:373)eti(cid:373)es fi(cid:374)ds (cid:449)hat o(cid:374)e is (cid:374)ot looki(cid:374)g for(cid:863) Widespread and indiscriminate use of antibiotic leads to resistance of pathogens to antibiotics.
