MBG 1000 Lecture Notes - Lecture 8: Sister Chromatids, Spindle Apparatus, Dna Replication

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Each chromosome consists of 1 chromaid before s phase. One molecule of dna wrapped around a protein scafold = 1 chromaid. Every human somaic cell has 2 copes of 1 chromosome 1 through 22 and xx or xy. Each chromosome consist of 2 geneically idenical sister chromaids ater s phase. In g1 we would be a single chromaid. Each chromosome consist of 2 geneically idenical sister chromaids ater s phase (this is not two chromosomes, this is one chromosome) Ater s phase a somaic cell has 2 copies of chromosome 1, 2, 3 22 and xx and xy and every chromosome consists of two idenical sister chromaids. Ater dna duplicaion, the single gene that was duplicated in g1 now has a sister chromaid. In addiion to genes, chromosomes contain speciic dna sequences that has speciic funcions: centromere. Repeiive dna sequence located within the centromere. Binds to mitoic spindle via kinetochore proteins. Criical for us to separaion of chromosomes.

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