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The endocrine system is the second of the body"s regulatory systems, other being nervous system. Hormones are chemical messengers that are secreted from endocrine glands or tissues and exert a physiological control in target cells. Endocrine: hormone is one that is secreted into the blood stream and transported to the target cells where is produces a physiological effect. Autocrine: hormone that is secreted into extracellular fluid and acts upon the cell that produced it. Paracrine: hormone that exerts its effects on cells near its secretion site (excludes neurotransmitters), but not in the cells that produced it. It acts within the organ where it is produced. Autocrine and paracrine hormones do not enter bloodstream. Generally hormones are primarily concerned with control of metabolism functions such as; rates of chemical reactions, the transport of substances through plasma, or some aspect of cellular metabolism like growth or secretion.

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