BIOM 3200 Lecture Notes - Lecture 5: Superior Vena Cava, Pulmonary Valve, Tricuspid Valve

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Lymphatic circuit collects interstitial fluid from body & brings it back to venous circulation: also plays major role in immune system, heart is in the center, providing driving force for blood distribution thru circulatory system. The heart: most critical component of cardiovascular system bc provides driving force for circulation. Myocardial nerves & myocardial (cid:862)pacemaker(cid:863) activity: normal heart beat is triggered by sinoatrial (sa) node specialized region of right atrium. Ca2+ flows in from extracellular fluid (ecf: produces rising (depolarizing) phase of action potential, which peaks slightly about 0mv, at this point, k+ channels open, making interior of plasma membrane increasingly negative. & creates falling (repolarizing) phase of action potential: when repolarization is complete, k+ channels close & pacemaker potential starts over, on its way to producing next heartbeat. Purkinje fibers at speed of ~4m/sec: consequently, entire ventricular myocardium depolarizes within 200msec after sa node fires, causing all muscle fibers in ventricles to contract nearly synchronously.

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