BIOL 1090 Lecture Notes - Lecture 19: Transmembrane Protein, Endomembrane System, Lysosome

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Er is an inter-connected network of membrane enclosed tubules and latened sacs (it is reicular-folded over and over) Interior (=lumen) is separate from the cytosol-recall diference between cytosol and cytoplasm. Er membrane is coninuous with the outer membrane of the. Funcions of smooth er (ser): speciic funcion in speciic cells. Producion of steroid hormones (e. g. endocrine cells are abundant in ser) Detoxiicaion (e. g. liver cells are abundant in ser). Contain enzymes that modify foreign compounds (oxygenases, cytochrome p450) In muscle cells, it is called sarcoplasmic reiculum) Can be connected to the rough er as well, since the smooth er is just er without ribosomes. Diferent types of proteins within the ser may be diferent from rer as it has diferent types of enzymes that do diferent jobs such as break down enzymes. Protein synthesis, modiicaion & transport-for proteins targeted" to er. There are no ribosomes in the lumen of the er, they are localized in the cytosol.

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