BIOL 1090 Lecture Notes - Lecture 9: Cytoskeleton, Cell Membrane, Chemiosmosis

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Usually depicted as oval, double membrane organelles, mitochondria undergo rounds of fusion & fission & their shape can change to be considered tubular! Nucleoid imm associated but not membrane bound. Mitochondria have two membranes: outer mitochondrial membrane (omm) (high lipid, low protein, contains many enzymes with diverse metabolic functions, porins. When open, membrane is freely permeable (e. g. to atp) large channel proteins: inner mitochondrial membrane (imm, high protein ratio (3:1, double layered folds = cristae, cristae: Increase membrane surface area: contain machinery for aerobic respiration and atp formation, rich in phospholipid called cardiolipin (characteristic of bacterial membranes) Aqueous compartments of mitochondria: inter-membrane space, matrix, high [protein] gel- like consistency, mitochondrial ribosomes. Encodes polypeptides that are integrated into the imm, ribosomes, trna. Presence of too much energy is going to cause the mitochondria to explode this is why they fuse (fission) together to get back to acceptable gradient. Chemiosmosis chemicals flowing through a membrane due to imbalance of charge.

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