BIOL 1090 Lecture Notes - Lecture 1: Microtubule, G1 Phase, Telomere

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Mitotic cells in the adult body would be considered stem cells. Cell organelles and cytoplasmic contents are divided more or less equally between daughter cells. Er and golgi complex are fragmented during division and reformed in the dauther cells. Mitochondria and chloroplats are randomly divided between daughter cells. Nuclear chromosomes must be duplicated exactly and distributed equally to daughter cells. Cell cycle time can be 30 min to several years depending on the stem cell. Interphase: the time between successive mitoses (g1 + s + g2) *cells that are not actively cycling may exit the cell cycle. From g1 they enter a state called g0, quiescent (ex. Facilitate replication of the end of the linear dna. Provide the point of attachment of chromosomes to microtubules in the mitotic spindle. The role of cohesin and condesin in the formation of mitotic chromosomes. Cohesin: ring shaped protein added to the dna at interphase.

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