BIOL 1090 Lecture Notes - Lecture 22: Cytoplasm, Nucleoplasm, Intermediate Filament
12 Oct 2016
School
Department
Course
Professor
Document Summary
Can be any shape, not just round; sometimes may appear to have two hemispheres, sometimes it is oblong (like an egg) All have heterochromatin, nuclear envelope, and nucleolus. Storage, replication & repair of genetic material. Chromatin is associated with the inner side of the nuclear envelope: in an expanded state. Nuclear envelope: nuclear membrane, nuclear lamina, nuclear pores. Nuclear content: chromatin, nucleoplasm, nuclear matrix, nucleolus. 2 parallel phospholipid bilayers (2 membrane system: outer membrane. Binds ribosomes and is continuous with rough er (rer: inner membrane. Contains integral membrane proteins that connect to nuclear lamina. A lot of embedded proteins: membranes separated by 10-50nm. Separates the outer side of the nucleus. Separates nuclear content from cytoplasm: separates transcription & translation. Selective barrier: allows limited movement of molecules between nucleus and cytoplasm. Integrity regulated (maintained) by phosphorylation: bound to inner surface of nuclear envelope (ne) Via prenyl group linked to lamin polypeptide.
