BIOL 1050 Lecture Notes - Lecture 2: Tetraodontidae, Local Anesthetic, Axon Terminal

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Local anaesthetic usage: tetrodoxin can act as human pain relief. Monday, november 13, 2017: possible test question. Dopamine: affects brain synapses in control of body movements; linked to sensations of pleasure (ex. Serotonin: regulates temperature and sensory perception; involved in mood control: depression, tryptophan (amino acid for serotonin) affected, use this information to produce drugs to alter action of neurotransmitter, specific neurotransmitters for brain or gut. Examples: acetylcholine in action, acetylcholine is a neurotransmitter that crosses a neuromuscular junction, excites muscle-cell membrane, causing depolarization and contraction of muscle fibre, locomotion depends on muscles. Monday, november 13, 2017: stimulates skeletal muscle cells. Involved in eating, circadian rhythmicity, neuroendocrine function, sleep: 5-ht synthesized from tryptophan, precursor of hormone melatonin, much of serotonin (95%) is produced in the gut, understand side-effects better. Reflexes: receptor receives sensory input, which it sends to the brain for processing; brain analyzes the information and determines appropriate output.

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