BIOC 2580 Lecture Notes - Lecture 6: Enol, Purine, Heterocyclic Compound

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Linear polymers made by connecting nucleotides via phosphodiester bonds. Sugar = d-2-deoxyribose for dna or d-ribose for rna. Sugars linked together by phosphates = form the backbone of nucleic acids (cid:498)sugar-phosphate backbone. **d-2-deoxyribose is unusual bc o( of c(cid:884) replaces with ( ~ (cid:498)deoxy(cid:499) *c atoms numbered w/ prime (cid:523)(cid:494)(cid:524) to distinguish them from atoms of the bases. Nitrogenous bases of nucleic acids are derivatives of. Heterocycles = aromatic rings containing non-c atoms (n, o, s) **n atoms only found in rings of nucleic acid bases. Tautomers = isomers that differ by the shift of an h atom and a double bond. *the amino + keto form predominates thymine (dna) (5-methyluracil) Purine ring joined together, bicyclic heterocycle (2 rings) Base joined to sugar via glycosidic bond to form a nucleoside. Special type of glycoside found in nucleic acids. Glycosidic bond sometimes called a glycosylic bond to designate the c-n linkage. Linking purine and pyrimidine bases to the sugars.

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