KNES 433 Lecture Notes - Lecture 20: Glycated Hemoglobin, Diabetic Coma, Insulin Resistance
19 Jul 2018
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Lecture 20 diabetes: prevalence = 171 million people worldwide (projected to double by 2030). Diabetes microvascular and macrovascular consequences, rate of atherosclerosis, mi & death. Measurement: glycosylated hemoglobin (hba1c: hba1c means glucose attached to hemoglobin. Bg measure last three months: diabetics = bg fluctuations. Careful w/exercise in diabetics who are on insulin because of possibility of diabetic coma if bg drops too low, which tends to be more of a problem in t1dm. T2dm tend to have high bg levels (bad food/low pa: pancreas = gland below stomach = insulin prod. T1dm = no production, t2dm = insensitivity/insufficient. Pancreas release small amounts of insulin consistently and bigger amounts after meals insulin goes through blood stream to target tissues and regulates glucose entry. Exercise = bg: hyperglycemia = abnormally high levels of bg, to bg, take insulin/oral medications + exercise. To bg, consume foods (particularly w/higher glycemic index: cu hing" yndrome = hypercortisolism = prolonged exposure to cortisol.
