KNES 433 Lecture Notes - Lecture 16: Arterial Stiffness, Pulmonary Artery, Apolipoprotein B
11 Apr 2018
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Lecture 16 case study: clarence de mar (7x boston marathon winner). 1910 = finished 2nd but advised to stop running because of heart murmur. Asymptomatic and apparently healthy 64-year-old marathon runner underwent comprehensive cv risk assessment as part of a prospective study on calcified coronary plaque burden in master marathon runners. His profile suggested a low 10-year cardiovascular risk. 2nd decade of life it goes up a bit and then plateaus, then it may more and more throughout the years. Fhx of arterial htn may cause arterial stiffness from birth or may become stiff from an overgrowth of cells and may make it easier to form blood clots in the arteries. Small arteries in lungs are narrow ( resistance to flow in lungs). Ldl level = 3. 0 = less than normal = excellent! Tg = low = fuel source for marathon runners so this is normal!
