KNES 303 Lecture Notes - Lecture 7: Red Blood Cell, Vo2 Max, Cardiac Output
Document Summary
Knes 303 lecture 7 physiological determinants of aerobic function. Mitochondrial respiration may not be a determining factor once you have achieved a high level of fitness. In trained individuals, the absence of a relationship may represent the fact that o2 extraction capacity exceeds. O2 delivery capacity: vo2max mainly limited by an insufficient o2 delivery, mitochondria capacity exceeds the o2 delivery capacity. Increased reliance on fat metabolism so we have delayed reliance on anaerobic energy sources. Physiological implications: when the intensity is really high, aerobic systems (oxidative phosphorylation) may not be able to provide all the. Atp required so we have more and more activation of anaerobic systems (pcr being used, lactate being produced, accumulation of h+, ph dropping, glycolysis occurring, etc. ) Fatigue: when intensity is increased alteration of the adp/atp ratio (build-up of adp and depletion of atp) is a potent stimulus that activates further usage of pcr and breakdown of glycogen and acceleration of glycolysis.