CMMB 431 Lecture Notes - Lecture 18: Shigella, Venn Diagram, Ubiquitin Ligase
25 Jun 2020
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Document Summary
Adapted to live in our gut temperature and ph. Close relative of e. coli are salmonella and shigella. Ability to ferment lactose was used to distinguish between these two: coli k-12 laboratory workhorse. E. coli is used to propagate dna, purify proteins, genetic manipulation of dna. Used openly because we have genetic tools to manipulate e. coli, easy to grow, and is the cheapest way to produce recombinant proteins. Huge diversity in pathogenic strains of e. coli. Given the pathogenic outcomes associated with this bacteria and the places where infections occur, we recognize this many different strains. Tells us that we invent these names to bring order to something that is not prone to proper classi cation. E. coli infects all parts of the body, not just a certain location, as would be thought. This is due to the amount of diversity, due to which the bacteria can live in multiple environments of the body.
