CMMB 431 Lecture Notes - Lecture 4: Cell Membrane, Swarming Motility, Pseudomonas Aeruginosa

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Inoculation: take a small amount of pathogen, make small incision in skin, introduce the pathogen to trigger an immune response. This is risky because it can make you sick if immune response fails. Use cow pox which is a similar pathogen to cause a similar immune response as small pox. Vaccination against small pox made by edward jenner. Cow pox is an example of an attenuated vaccine. Advantage: can load it up with different antigens for multiple pathogens at the same time, and use just one vaccine. Potential for carcinogenesis is dna is not inserted in the correct location. People who haven"t been immunized (eg. allergic people) will be protected by those surrounding you that are immunized. 2 children in samoa died because nurses in school gave wrong vaccine, resulting in anti- vaxxers ying to samoa and convincing population that vaccines are not safe. Immunocompromised people can be those who have undergone chemo, have diabetic ulcers.

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