ZOOL342 Lecture Notes - Lecture 3: Nernst Equation, Resting Potential, Membrane Potential

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Nernst equation: ek= is volts and convert into mv for cells, so 0. 025v to 25mv, convert ln to log: ek= 58 log (outside)/(inside) 2 and 3 equations are usually used in constant room temperature. Potassium is always less outside and high inside and cl- is high outside than inside. The positive and negative charges in and outside of the cell needs to balance out, Resting mv= -85mv: change [k+] double k+, so increase from 3 to 6, and take away 3 positive charges from na, to maintain electrical neutrality. Relative volume of one, potassium goes inside the cell and cl- follows k+ and goes inside the cell down its gradient. This causes the cell volume to increase and at the new equilibrium the membrane potential is -68mv. The volume increased so the effective concentration of na is smaller even though it was not allowed to move. little movement of cl- has great effect on the inside of the cell.

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