MICRB265 Lecture Notes - Lecture 1: Edward Jenner, Smallpox, Microbiological Culture
10 Sep 2018
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Document Summary
Discovered the method that isolated a pure bacterial culture. Proved that diseases are caused by specific microorganisms. It must cause the disease in the healthy individual. Remove tissue or blood sample: the suspected pathogen must be extracted from the now diseased organism to be shown same as before. The suspected pathogen might be present in both healthy and diseased mammals, but more in the diseased individual. It might only be a microorganism taking advantage of the breeding ground. Repeating the experiment on other animals and in different labs must be done to confirm results. Slow growing organisms will be overtaken by fast growing ones. Organisms that do not grow on selected media will fail. Isolated colonies arrive from a single cell, hence colonies have only one cell. He observed that milk maids were resistant to small pox. Alexander fleming discovered penicillin- the first antibiotic which came from the fungi penicillium. Waksman and schatz discovered streptomycin in soil bacteria.
