BIOCH200 Lecture Notes - Lecture 8: Skeletal Muscle, Anabolism, Nicotinamide Adenine Dinucleotide
23 Dec 2019
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Why is atp a "high energy" molecule: atp + h2o -> adp + p" + h, g = -30kj/mol, substrates unstable, products more stable, releases energy when released, as then it has, decreased electrostatic repulsion, has resonance stabilization. Whats the difference: proton: no electrons, + charge, hydrogen atom: one electron, no charge, hydride ion: 2 electrons, negative charge. Cofactors: nad+, the net charge is -1, the "+" is the charge on its ring. Dietary macromolecules: not significant fuel source, nucleic acids, proteins, significant fuel source, polysaccharides (complex carbs, most significant fuel source, triacylglycerol (fats) The balance between storage and mobilization of fuel molecules. Excess fuels are stored: carbohydrates are stored as glycogen, stores in the liver (hepatocytes, stored in the skeletal muscles (myocytes, fatty acids are stored as fat (triacylglycerol, stored in adipocytes. Free energy changes: standard free energy of a reaction is a thermodynamic term.
