HSCI 324 Lecture Notes - Lecture 3: Binomial Theorem, Phenylketonuria, Panmixia
2 Feb 2021
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Document Summary
Knowing the recessive allele frequency allows for determination of carriers, of disorder genes, in the population. models. Let"s consider a deme with the genotype frequencies. 100 aa, 200 aa and 100 aa, therefore the allele frequencies are 0. 5 for a and 0. 5 for a. 200 aa, 0 for aa and 200 aa, the allele frequencies would also be 0. 5 for a and 0. 5 for a. The gene pool does not predict the genotype. Laws of meiosis describes the transition from a diploid stage of life to haploid cells. Following fertilization, a diploid individual will develop: many factors will influence the probabilities of specific gametes coming together in fertilization events to produce a population structure. Many factors work collectively to influence the outcome of these probabilities. Infinite population: random mating of diploids (random union of gametes, non-overlapping generations, males and females have similar allele frequencies, no selection, no mutation, no migration, natural selection does not affect the alleles under consideration.
