BPK 375 Lecture Notes - Lecture 8: Thyroid, Anterior Pituitary, Insulin-Like Growth Factor 1
27 Oct 2016
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Document Summary
Week 8 unit 5 hormonal control and somatic & sexual development. Autocrine: the cell that produces and releases the hormone is also the cell in which the hormone acts. Paracrine: the cell produces a signal to alter the behaviour or cause differentiation of nearby cells. The signaling molecules (paracrine factors) act locally and diffuse over a relatively short distance. Paracrine signaling is common during development, where a cell"s fate is determined by interactions with nearby cells. Endocrine: hormones that travel via the circulatory system to influence cells further away. Hypothalamic hormones are secreted to the anterior lobe by way of a special capillary system, called the hypothalamic-hypophysial portal system. The anterior pituitary synthesizes and secretes: growth hormone ("hgh" or "gh" or somatotropin): released under influence of hypothalamic growth hormone-releasing factor (ghrf), inhibited by hypothalamic somatostatin, thyroid-stimulating hormone (tsh), released under influence of hypothalamic. Adrenocorticotropic hormone (acth): released under influence of hypothalamic.
