BISC 101 Lecture Notes - Lecture 1: Lipid Bilayer, Nuclear Lamina, Golgi Apparatus
14 Mar 2016
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Document Summary
Chromosomes found within membrane bound nucleoid, 1-100 small dna molecules (plasmids) Contains chromosomes (dna) that carries genetic information. Nucleolus: site of manufacture of rrna and assembly of ribosomal sub-units. Nuclear envelope: double lipid bilayer supported by lattice-lie sheet called nuclear lamina. Endomembrane system: regulates protein traffic and performs metabolic functions. Rough er: protein processing, folding, modification and packaging. Smooth er: lipid/steroid synthesis, detoxification of drugs, calcium storage. Golgi apparatus: receives, modifies, stores and ships products from er. Attached to er: makes proteins for export in membrane bound vesicles. Free in cytosol: make proteins that function in cell (enzymes) Cytoskeleton: network of fibers that organizes structure and activity of cell. Cilia/flagella utilise microtubules and motor protein (dynein) to move cell. 9 doublet microtubules + 2 single microtubules. Whole structure: axoneme, attached to cell by basal body. Doublet microtubules connected by spokes, connected by dynein for movement. Passive transport (diffusion, osmosis): does not require energy.
