Nursing HDP401 Lecture Notes - Lecture 2: Benign Tumor, Contact Inhibition, Metastasis
3 Feb 2018
School
Department
Course
Professor
Document Summary
Promotion stage - enhancing/enable the developing of cancer but do not initiate: cigarette smoke, high fat diets, hormones and growth promoters. Progression - after the tumour of cells has formed it changes to increase the level of damage/spread or growth possible: enzymes, hormones. Increased ability to redirect blood flow to tumour. The genes that regulate cell cycle are often involved when they mutate. 2 main categories: protooncogene - normal/regulatory genes that act like an on switch to increase cell reproduction. If altered and don"t turn off they are called oncogenes. Some that have been identified like; her2 (membrane receptor proteins), ras: tumour suppressor genes - normally turn off cell proliferation, unless they are mutated like p53, Irregular in colour: little or no adhesiveness, cohesion, and contact inhibition, highly metastasis (moves, can be harmful in many ways, replace normal tissue --> loss of function.
