PSY 215 Lecture Notes - Lecture 3: Benzodiazepine, Etiology, Ketamine

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Major substances of abuse: depressants, opioids, and alcohol. The brain: neuroanatomy, left and right hemisphere. Right controls left side, left controls the right side: left hemisphere. Hindbrain, midbrain, forebrain: forebrain role, cerebral hemispheres and cortex. Thalamus: relay centre to and from the cortex. Hypothalamus: regulates autonomic functions: thirst, hunger, sexual drive, temperature, sleep, cellular unit of the brain, neuron. Axon, dendrites, soma, nt, neuropeptides, neuromodulators (hormones) synapse. Major nt"s: dopamine, norepinephrine, epinephrine, serotonin, acetylcholine, histamine, gaba, glycine, glutamate, adenosine. Vta, na and mfb), ventral tegmental nucleus, na, locus coerulus. Scheduling of substances: addictive drugs produce strong neurochemical change, these changes underlie the basis of abuse and dependence, tough regulations to reduce access, see table 2. 2. Schedule i: high abuse potential, restricted access. Schedule v: low abuse potential, medical use accepted. Depressants: alcohol: cns depressant, produces euphoria, activation of endorphin reward system, strong abusive potential, 90% adults consume.

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