ENH 220 Lecture Notes - Lecture 8: Atypical Pneumonia, Pneumocystis Jirovecii, Airway Obstruction

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Oxygen delivery: a cooperative effort: respiratory system oxygenates blood and removes carbon dioxide, circulatory system transports gases in the bloodstream. Lung: structure and function: system of tubes conduct air into and out of the lungs. Gas exchange: two functions of respiration, ventilation: movement of air into and out of lungs. Expiration: gas exchange between alveolar air and pulmonary capillaries. Partial pressure: part of total atmospheric pressure exerted by a gas. = 0. 20 x 760 mmhg = 152 mmhg: gases diffuse between blood, tissues, and pulmonary alveoli due to differences in their partial pressures. Alveolar air (cid:1371) p02 105 mmhg p02 20 mmhg (cid:1373) pc02 35 mmhg pc02 60 mmhg: requirements for efficient gas exchange. Large capillary surface area in contact with alveolar membrane. The pleural cavity: pleura: thin membrane covering lungs (visceral pleura) and internal surface of the chest wall (parietal pleura) Intrapleural pressure: pressure within pleural cavity: pleural cavity: potential space between lungs and chest wall.

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